The half-acre site of the famed Amrheins restaurant at 80 West Broadway in South Boston is on sale as a development opportunity. Its listing brokerage, Newmark Knight Frank, expects it to fetch as much as $20 million amid competitive bidding.

A deal could come before Thanksgiving. As to what would eventually supplant Amrheins, that is still very much in the air. But there are some possibilities, the likelier among them a conversion to either an office building or a life sciences complex.

And Amrheins, said to be the oldest restaurant and bar in South Boston, could itself survive as part of a redevelopment. Right now, residential does not appear to be in the mix.

Whatever replaces the restaurant and its parking lot will enjoy an enviable location—at the corner of A Street and West Broadway, and a short jaunt to the busy, busy Red Line’s Broadway stop. Stay tuned.

• Famed Amrheins restaurant site up for sale [Real Reporter]
• Amrheins in Southie up for sale [Globe]
• Living along the Red Line: 6 new condo and apartment developments, mapped [Curbed Boston]